Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------------------------------------------------------------------------------------------------------------------------------------MEIPIKIIQASKSDLPEIGALQTSSFPA-------EKQQLSHILEESIRKCADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLL-AALKEVAVELDYKGIRLES---PDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ 1P0H Chain:A ((6-313)) ALDWRSALTADEQRSVRALVTATTAVDGVAPVGEQVLRELGQQRTEHLLVAGSRPGGPIIGYLNLSPPGGAMAELVVHPQSRRRGIGTAMARAALAKTAGRNQFWAHGTLDPARATASALGLVGVRELIQMRRPLRDIPEPTIPDGVVIRTYA-GTSDDAELLRVNNAAFAGHPEQGGWTAVQLAERRGEAWFD-PDGLILAFGDGRLLGFHWTKVHPDHPGLGEVYVLGVDPAAQRRGLGQMLTSIGIVSLARRLVEPAVLLYVESDNVAAVRTYQSLGFTTYSVDTAYAL-----------------

General information: TITO was launched using: RESULT: Template: 1P0H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 552 -16754 -30.35 -124.10 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -30.35 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.451

(partial model without unconserved sides chains): PDB file : Tito_1P0H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1P0H-query.scw PDB file : Tito_Scwrl_1P0H.pdb: