Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFEKIRSDMNPHQAYRIKKLQCQLDMAESYEEWKSFALKLDEETGAQEWKFDNSSPYFDAELISYRYTLLKRYRQQHRT-LDLIYLLKEGLTYDIANIGHPMLFAATHVGTKKLIEDYIEE-VSQSLAYIASSECITFQRKEKIEFFENCEKAYGQPALMFSGGATLGLFHTGVCKALIEQDLMPKVLSGSSAGAIMTG-MLGISASEDIQNLLNGEQFFSDAFHFRKLRELIKGNGGIADVHY---LK-KFLIENLGDLTFEEAFKKSGLNINVAVAPYDATENPRIMNAIMTPNVLV-----WSAVLASCAVPVLFPPVRLTSKRYDGEHTPYMANTKWVDGSVRSDFPQERMARLYNLNYTIASQVNPHVVPFMQDDARRFRKDVLSWPE-RILRRQGKVLSMGLMDFTRQRLGAISPVRR-LLDHG-YGVVGQR-YYGDVNIIAKYSLKHYAYTLQNPRP------------HLF-KRLQREGERATWPKISSIETHARIGKTIQHCLEVLRFEEKKQQPESYYAEA 1OXW Chain:A ((25-384)) ----------------------------------------------------------------------------LGEMVTVLSIDGGG------------IRGIIPATILEFLEGQLQEMDNNADARLADY---------------------------------------------------FDVIGGTSTGGLLTAMISTPNENNRPFAA----AKEIVPFYFEHGPQIFNPSGQILGPKYDGKYLMQVLQEKLGETRVHQALT-----EVVISSFDIKTNKPVIFTKSNLANSPELDAKMYDISYSTAAAPTYFPPHYFVTNTSNGD----EYEFNLVDGAVAT-------------VADPALLSISVATRLAQKDPAFASIRSLNYKKMLLLSLGTGTTSEFDKTYTAKEAATWTAVHWMLVIQKMTDAASSYMTDYYLSTAFQALDSKNNYLRVQENALTGTTTEMDDASEANMELLVQVGENLLKKPVSEDNPE-TYEEALKRFAKLLSDRKKLRANKA-----

General information: TITO was launched using: RESULT: Template: 1OXW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1892 69479 36.72 209.91 target 2D structure prediction score : 0.38 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 36.72 2D Compatibility (Sec. Struct. Predict.) : 0.38 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.223

(partial model without unconserved sides chains): PDB file : Tito_1OXW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OXW-query.scw PDB file : Tito_Scwrl_1OXW.pdb: