Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALTNEEILNAVAEKTVLELVELISAFEEKFNVSAAAVAVA--APAGG-A-AAAAEEQSEFNVELTSFGANKVAVIKAVREATGLGLKEAKDLVEGAP---QVL-KEGVSKEEGEELKKKLEEAGATVTLK 1DD3 Chain:A ((2-128)) ---TIDEIIEAIEKLTVSELAELVKKLEDKFGVTAAAPVAVAAAPVAGAAAGAAQEEKTEFDVVLKSFGQNKIQVIKVVREITGLGLKEAKDLVEKAGSPDA-VIKSGVSKEEAEEIKKKLEEAGAEVELK

General information: TITO was launched using: RESULT: Template: 1DD3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 348 21141 60.75 177.66 target 2D structure prediction score : 0.81 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : 60.75 2D Compatibility (Sec. Struct. Predict.) : 0.81 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.680

(partial model without unconserved sides chains): PDB file : Tito_1DD3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DD3-query.scw PDB file : Tito_Scwrl_1DD3.pdb: