Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPRIKVLPHAQFCPEGAEFEVEQNANLCQSLLNKGI-KIEHACDMSCACTTCHVIVRKGF-DSLEEMNDVEADLLDRAWG-LEPDSRLSCQVKVVDE--DLEIEIPKYTINHASENH 3LB8 Chain:C ((14-102)) -----------------ELDVADGVSLMQAAVSNGIYDIVGDCGGSASCATCHVYVNEAFTDKVPAANEREIGMLESVTAELKPNSRLSCQIIMTPELDGIVVDVP-----------

General information: TITO was launched using: RESULT: Template: 3LB8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 336 -7361 -21.91 -87.63 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain C : 0.74 3D Compatibility (PKB) : -21.91 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_3LB8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LB8-query.scw PDB file : Tito_Scwrl_3LB8.pdb: