Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSTILVIHGPNLNLLGKREPEVYGHLTLDNINQQLIAQAEQASITLDTFQSNWEGAIVDRIHQAQTEGVKLIIINPAALTHTSVALRDALLGVAIPFIEVHLSNVHAREAFRHHSYLSDKAIGVICGLGAKGYSFALDYAIEKIQPSNPN 1UQR Chain:L ((4-144)) ----ILLLNGPNLNMLGK--------QTLSDIEQHLQQSAQAQGYELDYFQANGEESLINRIHQA-FQNTDFIIINPGAFTHTSVAIRDALLAVSIPFIEVHLSNVHAREPFRHHSYLSDVAKGVICGLGAKGYDYALDFAISELQ-----

General information: TITO was launched using: RESULT: Template: 1UQR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain L - contact count / total energy / energy per contact / energy per residue : 657 -122962 -187.16 -924.52 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain L : 0.88 3D Compatibility (PKB) : -187.16 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.598

(partial model without unconserved sides chains): PDB file : Tito_1UQR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1UQR-query.scw PDB file : Tito_Scwrl_1UQR.pdb: