Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MREYKGLKIAVAGTGYVGLSIATLLAQ-SHTVTAVDIIPEKVELINNKKSPIQDDYIEMYLAK--KELDLMATVDGVSAYKDADFVVIAAPTNYDSKKNFFDTSAVEAVIKLVMEV-NPEAIMVIKSTIPVGYTASIREKTG---------SKNIIFSPEFLRESKALYDNLYPSRIIVGTDMEDERLVEAAQTFAKLLQEGAIKENVDTLFMGFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQQIINGVCRDPRIGT--HYNNPSFGYGGYCLPKDTKQLLANY--EDVPENLIEAIVESNRTRKNFIADRVLELAGAYEANSHWDASKEKKVVIGVYRLTMKSNSDNFRQSSIQGVMKRVKAKGTTVVIYEPSLKDGEIF---FGSKVVNDLDQFKAMCDSIIANRYDTCLDDIK------------EKVYTRDIFQRD 4XR9 Chain:A ((11-438)) -GEPSPLKVVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPEPGLAGAVRDLAATGRLTASTS-YDPVGAADVVIVTVGTPTDAG-HEMVTDQLVAACEQIAPRLRAGQLVILKSTVSPGTTRTLVAPLLESGGLVHERDFGLAFCPERLAEGVALAQVRTLPV-VVGGCGPR-----SAAAAERFWRSAL-G-VDVRQVPSAESAEVVKLATNWWIDANVAIANELARYCAVLGVDVLDVIGAANTLPKGSSMVNLLLPGVGVGGSCLTKDPWMAWRDGRDRGVSLRTVETARAVNDDMPRHTAAVIADELVK-----L--GRDRNDTTIAVLGAAFKNDTGDVRNTPVRGVVAALRDSGFRVRIFDPLADPA-EIVARFGTAPAASLDEAVSGAGCLAFLAGHRQFHELDFGALAERVDEPCLVFDGRMHLPP-

General information: TITO was launched using: RESULT: Template: 4XR9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2139 -16899 -7.90 -42.67 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -7.90 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.453

(partial model without unconserved sides chains): PDB file : Tito_4XR9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4XR9-query.scw PDB file : Tito_Scwrl_4XR9.pdb: