Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIPQGHKIALGDLKAGDNVIKYGYPIGHVTT-DVTAGQWLHTHNVKTN--LSGELDYRYEKDVHPSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFDHITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGEYDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLSGITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFKQYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLSLLQAPGNDLVAASALASSDCQLVLFTTGRGTPFG-SYVPTVKVSTNTTLFERKGHWMDFNAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL 5H7I Chain:C ((15-604)) -----VPVIDLNRVSD-EEQLLPVVRAILLQHDTFLLKNYANKAVLDALLAGLTTKDLPDTSQGFDANFTGTLPLEDDVWLEQYIFDTDPQLRFDRKCRNESLCSIYSRLFKLGLFFAQLCVKSVVSSAELQDCIST--------SHYATKLTRYFGVLTIFPCAKAIR--YKPSTMATTDNSWVSIDEPDCLLFHTGTLLARWSQGMHTTSP-----LQIDPRANIVSLTIWPSILRLQDAMKFVKELFTVCETVLSLNALSRSTGV---------------------------PPELHVLLPQISSMMKRKIVQDDILKLLTIWS------DAYVVELNSRGELTMNLPKRDN----LTTLTNKSRTLAFVERAESWYQQVIASSQRQKRYQQFLAMKMTQVFDIL-----------FSLTRGQPYTETYLSSLIVDSLQDSTKEASEILAGLQGIL---PMDISVHQVDGGLKVYRWNSLDKNRFSKLLQI--HKSKQQD

General information: TITO was launched using: RESULT: Template: 5H7I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1795 12633 7.04 29.72 target 2D structure prediction score : 0.34 Monomeric hydrophicity matching model chain C : 0.60 3D Compatibility (PKB) : 7.04 2D Compatibility (Sec. Struct. Predict.) : 0.34 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.024

(partial model without unconserved sides chains): PDB file : Tito_5H7I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5H7I-query.scw PDB file : Tito_Scwrl_5H7I.pdb: