Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLALFDLDHTLLNTDSDHSWGEFLVNEG-LV---DPV-HHRQMNDKFYED-YK-AGQLDPYAYNEFVFGFLTKHDNNYLTELHQLFMEKVIR--------PKMRPKGFDAIKKHQDLGHTIVGITATSDFITAPIFR-EFGI--TEILATNAEV----ADGKYT----GKVAGLACYQKGKLARLEAWLDGRSVSESWAYSDSINDRFLLEYATHAI------AV--------------NPDDRL---EKLAQEHNWEIQDWSI 4OVY Chain:A ((36-295)) ERIVTFDNDGTLWCEQPMYVQLAFALDRVRLLADKHPEWRTEEPFRAVIEKDLPALAKLGAKGLTELTMATHAGMTDDEFENIVTEWIRKARHPKFHRPYTECVYQPMLELLAFLRQHEFKTFIVSGAGIEFMRPWAKEVYGIPPEQVIGSSVKLKYELRDGKPVLVRLAEL-NFIDDQAGKPVGIRQVI-G--RRPVMAVGNSDGDYEMLEYVTSGPANGLGLIVHHTDAVREFAYDRQSPFGRLDRALTDATSKGWIVIDMQ-

General information: TITO was launched using: RESULT: Template: 4OVY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1015 1397 1.38 6.62 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 1.38 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.498

(partial model without unconserved sides chains): PDB file : Tito_4OVY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OVY-query.scw PDB file : Tito_Scwrl_4OVY.pdb: