Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFTGIIESLGKVESLQSVGGDVRLRIQTD-LDMSDVHLGDSIATNGICLTVIEWGDNWYAADVSRESLNRTTLGNWKVGQRVNVEKAMLPTTRFGGHIVSGHVDGVGEITLVR-E-DARSIYFEVTAPVELAKYLAEKGSVTVDGISLTINHLRGNILSLNLIPHTAERTNIGTWQVGSQVNLEVDVLARYIERLLLGDKAAEQKTESNISMAFLAENGFLK 3DDY Chain:A ((1-184)) MFRGIVQGRGVIRSISKSEDSQRHGIAFPEGMFQLVDVDTVMLVNGCSNTVVRILGDMVYFDI-DQALGTTTFDGLKEGDQVNLEIHP---------GLTGNIKGTALVAAIEENDAGFSVLIDI--PKGLAENLTVKDDIGIDGISLPITDMSDSIITLNYSRDLLASTNIASLAKDVKVNVEILN-----------------------------------

General information: TITO was launched using: RESULT: Template: 3DDY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 946 -1994 -2.11 -11.59 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -2.11 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.387

(partial model without unconserved sides chains): PDB file : Tito_3DDY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DDY-query.scw PDB file : Tito_Scwrl_3DDY.pdb: