Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHIKEKTLDDLLNSTYTFILENGDHITA-SKGENFEVRNAVLTLENPRSRLSISE-TRSKLISCIGEFFWYLNGSDSLEFIEYYISDYRKY-IEYQID--------ENKPALGAYGPRIFGA---------------QNQFNKIIEVLKDKPTSRRAVISIYSKDDLLREDSRDIPCTCLLQFFIRNERLHLTATMRSNDAAIGLVHDIFSFTLIQELLLAKLIRYIPNLQLGEYTHIVGSLHIYKKI 5BY6 Chain:A ((35-255)) --------------------DHGVRKNDRTGIGTLSTFGTQSRYCLRDDIFPLLTTKRVFWRGVVEELLWFISGSTNAKQLSEKNVNIWDGNSSREFLDSRGLYNYEEGDLGPVYGFQWRHFGCPYSSMTADYKGKGYDQLQQCIKMIREEPESRRIIMTAWNPCDLE--KVALPPCHCFVQFYVADGELSCQMYQRSADMGLGVPFNIASYSLLTRMIAH-----ITSLKPGFFIHTIGDAHVYLTH

General information: TITO was launched using: RESULT: Template: 5BY6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 755 -6816 -9.03 -34.95 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -9.03 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.368

(partial model without unconserved sides chains): PDB file : Tito_5BY6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5BY6-query.scw PDB file : Tito_Scwrl_5BY6.pdb: