Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNHFQFQTVPNIISGLGSIQELQNVLASKTYRKLLLVTDAG-MIKNQLHLPILQILDTLKIEHVIYADVQADPPEQVVLDAANYAKQQNVDVIVGFGGGSSLDVAKVIALLAHPNQTQNLQEMYGVN-QVKTARLPLILIPTTAGTGSEVTPISIVTTGETT-KMGIVSPVLYADTAILDATFTQNLPAHITAATGIDAMVHAIEAYTSKHKKN-IYTDILAKHALKLLNHNLPKVLKNGNDLEARQNMLFGSMLAGQAFAN---SPVAAVHALAYPLGGHFHLSHGHTNALVLVEVLKFNAPYAKQYYAELMQW-LDPYSNGSTDGLCDLFIDHMQNHLDRSGLTLKLSDLGIEESSLPRLAQDAMLQTRLLQNNPRDMTETAALAIYQAIY 1OJ7 Chain:C ((22-408)) LNNFNLHTPTRILFGKGAIAGLREQIPH--DARVLITYGGGSVKKTGVLDQVLDALKG--MDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKP-VDAKIHDRFAEGILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNITEGS-DDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR

General information: TITO was launched using: RESULT: Template: 1OJ7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 2051 -62512 -30.48 -164.94 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain C : 0.74 3D Compatibility (PKB) : -30.48 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.490

(partial model without unconserved sides chains): PDB file : Tito_1OJ7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OJ7-query.scw PDB file : Tito_Scwrl_1OJ7.pdb: