Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTQYFFLFPKIDQKKNGLVFALLKRAKILNEQLGISPTIITTEYDRSLAENYWSLIATNLAPPSIGYLNLYADFQGTHLKLANKKIHDPAIEMFNSNILKTII----PFTYNQRFHDKNNKNYLYEIRQNDSITLRYVNTFKK-GVKTGRIIYDSYGYLSCIQVINPENQMIITETYYHTEGYPVIIKNYQLNEKNKNIVSNIFLFNKQGVINEVFETESQLIQYWFLKISQLYENDLMYILI-DRAIHFYEPLREI--KQENMRFIGTIHATHLNGHDIQNSTINRHYRSYFKYSNELDALVILTERQKQHIQQRFGMEEKLFVIPHIYEKTIDHVNFSNRDPMFCLTIARYDKAKNLDSLIRIFKKVVEVIPNAYLNIYGFGSEHNFLQSQIDEHQLNNHIKLMGYNENTDALYNKASLFLFSSRSEGFGMAVLEALCHGCPVVSYDIDYGPSDMIKHDENGYLVTFQDEESFAQKVVSLLKDEHKRLKLSENAYACI-QLTDQKQFALKWQELFQAIQ 4X7R Chain:A ((1-492)) -MKKIFMMVHELDVNKGGMTSSMFNRSKEFYD-ADIPADIVTFDYKGNYDEIIKALKKQGKMDRRTKMYNVFEYFKQISNNKHFKSNKLL---YKHISERLKNTIEIEESKGISRYFD--ITTRTYIAYIRKSKSEKVIDFFKDNKRIERFSFID--NKVHMKETFNVDNK-VCYQVFYDEKGYPYISRNINANNGA--VGKTYVLV-----NKKEFKNNLALCVYYLEKLIK--DSKD-SIMICDGPGSFPKMFNTNHKNAQKYGVIHVNHHENFDDTG----AFKKSEKYIIENANKINGVIVLTEAQRLDILNQFD-VENIFTISNFVKIHNAP--KHFQTEKIVGHISRMVPTKRIDLLIEVAELVVKKDNAVKFHIYGEGSVKDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTSQYEGQGLSMIEAMISKRPVVAFDIKYGPSDFIEDNKNGYLIENHNINDMADKILQLVNNDVLAAEFGSKARENIIEKYSTESILEKWLNLFN---

General information: TITO was launched using: RESULT: Template: 4X7R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2530 81333 32.15 168.39 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 32.15 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.498

(partial model without unconserved sides chains): PDB file : Tito_4X7R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4X7R-query.scw PDB file : Tito_Scwrl_4X7R.pdb: