Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence CIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAV-EP--YTKKELSAVTFPDIIRNYKVMAAEN 2Y3A Chain:B ((197-273)) -YVGKINRTQAEEMLSGKRDGTFLIRESS-Q-RGCYACSVVVDGD-TKHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHA----

General information: TITO was launched using: RESULT: Template: 2Y3A.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 264 -26390 -99.96 -356.61 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain B : 0.73 3D Compatibility (PKB) : -99.96 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.550

(partial model without unconserved sides chains): PDB file : Tito_2Y3A.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y3A-query.scw PDB file : Tito_Scwrl_2Y3A.pdb: