Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVATNGSPRPFIY-EENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAVNNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSI-------------------KS----LDDIGGKSTEVVQATTSAKQLEAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVIELP----SDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK 4P0I Chain:B ((3-255)) -----------------------------------DYKSITIATEGSYAPYNFKDAGGKLIGFDIDLGNDLCKRM-NIECKFVEQAWDGIIPSLTAGRYDAIMAAMGIQPAREKVIAFSRPYLLTPMTFLTTADSPLLKTQVAIENLPLDNITPEQKAELDKFTKIFEGVKFGVQAGTSHEAFMKQM---MPS--VQISTYDT-IDNVVMDLKAGRIDASLASVSFLKPLTDKPDNKDLKMFGPRMTGGLFGKG-VGVGIRKEDADLKALFDKAIDAAIADGTVQKLSQQWFGYDA--------

General information: TITO was launched using: RESULT: Template: 4P0I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1088 18436 16.94 81.94 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain B : 0.69 3D Compatibility (PKB) : 16.94 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.455

(partial model without unconserved sides chains): PDB file : Tito_4P0I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4P0I-query.scw PDB file : Tito_Scwrl_4P0I.pdb: