Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCPECGNQLKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHNFSSLPKIMSWDVETVRGVTVSIGRWR 1K78 Chain:A ((31-72)) ---------------------------------------------------------------------------------------------------RPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRY-------------------------------

General information: TITO was launched using: RESULT: Template: 1K78.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 115 -30129 -261.99 -717.36 target 2D structure prediction score : 0.79 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -261.99 2D Compatibility (Sec. Struct. Predict.) : 0.79 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.833

(partial model without unconserved sides chains): PDB file : Tito_1K78.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1K78-query.scw PDB file : Tito_Scwrl_1K78.pdb: