Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEEKKMKRFVRMGIDVGGTHTKAVAIDNAT-HEIIGKSSVKTTHDDVRGVAAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFLAKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGVDNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTEDSVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFEVGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGPRSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANVLGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKI-EPVILELADKYHLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERIIPSPSKEDIRSLKNEAMNKAIESG--ATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLTKEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKVQRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQLQLLMDLEVSTMEPEEEVIVVAGNIKQT 5UAO Chain:A ((21-539)) PADDDPGAIRTVGVIGGGTAGYLTALALKAKRPWLDVALVESADIPIIGVGEATVSYMVMFLH-HYLGIDPAEFYQHVRP----------TWKLGIRFEWGSRPEGFVAP-------FDWGTGS-VGLVGSLRETG--NVNEATLQAMLMTEDRVPVYRG------EGGHVSLMKY---------------LPFAYHM---------DNARLVRYLTELAARRG-VRHVDATVAEVRLDGPDHVGGLITTDGRRL--------------------HYDFYVDCTGFRSLLLEKALGIP---------FESYASSLFT-------------------------------DAAVTGTLAH--GGHLKPY--------------------TTATTMNAGWCWTIPTPESDHLGYVFSSAA-----------IDPDDAAAEMARRFPGVTREALVRFRSGRHREAWRGNVMAVGNS---------------YAFVEPLE-----SSGLLMIATAVQILVSLLPSSRRDPLPSDAANQALAHRWDAIRWFLSIHYRFNGRLD--------------TPFWKEARAETDISGIEPLLRLFAAGAPLTGRDSFTRYLADGAAPLFYG-LEGVDT--LLLGQEVPARLLPPREP------PEQWRARAAAARSLASRG---LRQSEALDAYAADPCLNAELLSD---SDSWAGERVAVRAG-----

General information: TITO was launched using: RESULT: Template: 5UAO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3087 -5511 -1.79 -10.70 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -1.79 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.219

(partial model without unconserved sides chains): PDB file : Tito_5UAO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5UAO-query.scw PDB file : Tito_Scwrl_5UAO.pdb: