Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGDYYDLLLQKSDSYHEKEWCTLLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKAILQMTEDGTEEIISTRSKVFQKLNMD-LDDLPLQELLELVQNNPGLLRRPIMIDDKRLQVGFNEDEIRRFLPRDVRQLELRQAQLMAGL 2KOK Chain:A ((3-119)) -------------------GSMSVTIYGIKNCDTMKKARIWLEDHGIDYTFHDYKKEGLDAETLDRFLKTVP--WEQLLNRAGTTFRKLPEDVRSNVDAASARELMLAQPSMVKRPVLERDGKLMVGFKPAQYEAYFK-----------------

General information: TITO was launched using: RESULT: Template: 2KOK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 382 -32461 -84.98 -279.83 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -84.98 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.702

(partial model without unconserved sides chains): PDB file : Tito_2KOK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2KOK-query.scw PDB file : Tito_Scwrl_2KOK.pdb: