Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIPQGHKIALGDLKAGDNVIKYGYPIGH-VTTDVTAGQWLHTH-----NVKTNL-S--GE-L-DYRYEKDVHPSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELI-VKQFKE--KHPDLG-QFDHITI-LKHPYGCSQLGKDHQNTREILADAVNHPNAGGV-LVFGLGCENNTVPEFKKILGEYDEE-RVKFLVAQDVYDEI------EQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGL-S----GITANPLLGAFSDYLIAQGGSTILTEV-PEMFGA------------------EQVLMARAE-----NEEVFDSIVDLINDFKQYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLSLLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDFNAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL 3L0I Chain:A ((23-347)) -----------------------------------------------------------------SFSNMVSAKKFYNKAIFTAPKAEVSVKTHIMRPIDFMLMGLREEFNLYSEDHLSAPGTIRLLREKN--------LLPEEQIARIESVYNQAMSKRFELHAEHEHDEMPYSDAKAMLDEVAKIRELGVQRVTRIENLENAKKLWDNANSML------EKGNISGYLKAANELHKFMKEKNLKEDDLRPELSDKTISPKGYAILQSLWGAASDYSRAAATLTESTVEPGLVSAVNKMSAFFMDCKLSPNERATPDPDFKVGKSKILVGIMQFIKDVADPTSKIWMHNTKALMNHKIAAIQKLERSNNVNDETLESVLSSKGENLSEYLSYKY-------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3L0I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1016 63183 62.19 240.24 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : 62.19 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.137

(partial model without unconserved sides chains): PDB file : Tito_3L0I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3L0I-query.scw PDB file : Tito_Scwrl_3L0I.pdb: