Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMAALAAVKNGAGLVTVGTDRENIPALHSHLPEAMAFALQDKQLLKEQLEKAEVVLLGPGLGDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSL--SFPSSQLILTPHQKEWEKLSGITIE--KQK-EDTTASALTSFPKGTILVEKGPATRVWQAGQSDYYQLQVGGPYQATGGMGDTLAGMIAGFVGQFR-QASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMKIICQQERVSKDKLV 3BGK Chain:A ((40-310)) ------LLTKKIIKPRPLNSHKGTFGRVLLIGGNYPYGGAIIMAALACVNSGAGLVTVATHKDNITALHSHLPEAMAFDMVEKDRLSEQITAADVVLMGPGLAEDDLAQTTFDVVWQAIEPKQTLIIDGSAINLLAKRK-AIWP-TKQIILTPHQKEWERLSGLTIPEQIEAATQTALAHFP---KETILVAKSHQTKIYQG--QKIGHIQVGGPYQATGGMGDTLAGMIAGFVAQFHTDR--FEVAAAAVFLHSYIADQLSKEAYVVLPTRISAEITRVMKEMS-----------

General information: TITO was launched using: RESULT: Template: 3BGK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1541 -113067 -73.37 -428.28 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -73.37 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.596

(partial model without unconserved sides chains): PDB file : Tito_3BGK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3BGK-query.scw PDB file : Tito_Scwrl_3BGK.pdb: