Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTNTQITEDRILILDFGSQYSQLIARRVREAGVYSEMYAFDMSEEDIRAFKPNGIILSGGPESVHEEGSPRAP----QVVFELGVPVLGICYGLQTMSEQLGGKVELGTVHEFGYAEVDIVK---------------------------RDQLIGNLQDRENQLHVWMSHGDKVSQIPEGFTITASTPSCPVAAVSDETRRFYGVQFHPEVTHTAKGEELLSNFVHKICGCGGLWTPEHIIDLRVEQLREQIGNEKVLLGLSGGVDSSVVAALLHKAIGDQLTCVFVDNGLLRLNEGDQVMQMFAENMGI--RVIRADAEARFLNALAGVTDPEAKRKIIGREFIEVFAEEARK----LDGVKFLAQGTIYPDVIESAASKQGKAHVIKSHHNVGGLPDDLAFELVEPLRDLFKDEVRKLGTTLGLPHSMIYRHPFPGPGLGVRILGEVKKEYADILRLADDIFMQELRDSGWYGKTAQAFAVFQPVKSVGVVGDGRRYAWVIALRAVETVDFMTARFAHLPYELVDKISTRIMNEIKDVSRVVYDVSSKPPATIEWE 3UOW Chain:A ((7-556)) --------YDKILVLNFGSQYFHLIVKRLNNIKIFSETKDYGVELKDIKDMNIKGVILSGGPYSVTEAGSPHLKKEVFEYFLEKKIPIFGICYGMQEIAVQMNGEVKKSKTSEYGCTDVNILRNDNINNITYCRNFSSAMDLYSNYKLMN-CCLFENIK--SDITTVWMNHNDEVTKIPENFYLVSSSENCLICSIYNKEYNIYGVQYHPEVYESLDGELMFYNFAYNICKCKK-FDPIRYHELELKNIEKYKHDHYVIAAMSGGIDSTVAAAYTHKIFKERFFGIFIDNGLLRKNEAENVYTFL-KSTFPDMNITKIDASENFLSNLQGVTDPEQKRKIIGKLFIEEFEKAVNNIDIDI-NKTFLLQGTLYPDIIESKCS--------------------LKFKLFEPFKYLFKDDVKTLSRELNLPEEITNRHPFPGPGLAIRVIGEINKHKLNILREVDDIFINDLKQYGLYNQISQAFAVLLSSKSV--------YDYVCVLRAVKTSSFMTANWYQIPYDILDKITTRILSEVKGVNRILYDVSSKPPATIEFE

General information: TITO was launched using: RESULT: Template: 3UOW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2544 -35024 -13.77 -72.97 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -13.77 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.506

(partial model without unconserved sides chains): PDB file : Tito_3UOW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UOW-query.scw PDB file : Tito_Scwrl_3UOW.pdb: