Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTEGVGLPLWLLAELTYRCLLQCPYCSNPLDYAQ-HKN-ELTTQEWFDVFDQARQMGAVQLGFS-GGEPLVRQDLEQLVAHAHQLGFYTNLVTSGMGLTEQRISHLKQAGLDHIQISFQ-ASDPVLNDA---LAGSKHAFEQKYEMCRLVKK-YDYPMVLNFVIHRHNIDQIDKIIE-LCLELNADTVELAICQFYGWAFLNRQGLLPT-QEQLIRAERITNEYREKLKAQNHPCKLIFVVPDY-YEERPKACMNGWGKIFFTVAPDGMALPCHAARQL-PISFPNVREQSLSRIWY-ESTGFNRFRGDAWMPEGCRSCPDK-DRDFGGCR-C-QAYMLTGDASNADP-VCGKSPYHQFIEQARAESEIDSSLEKLVFRNSRNSKQFTVQQNIPVQNIVDD 3QI7 Chain:A ((33-395)) ------------IIDDFKVAVVTQPLSENKVQYNMVEEMAKEYEEENKIDKTKVKQTIKHVVLPENFTSNIDSAINKIVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNLGVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMI----------KETCKNIGLPFVQVNTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVAEQSNPS----PIQTYPSVMGLKISEKDAQNYDKINDMISEKAKA---------------FGMSNRLGGYPMPMDAFLPSLAIYLATEMVKQDLTQEDVCDPDYLE-AFTELRFGIGSEFTPLTEVLYNYQSVILSQLIY-

General information: TITO was launched using: RESULT: Template: 3QI7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3 -584 -194.67 -1.71 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -194.67 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.58 QMean score : ?

(partial model without unconserved sides chains): PDB file : Tito_3QI7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QI7-query.scw PDB file : Tito_Scwrl_3QI7.pdb: