Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRTLSMNYLQDARQHVLQQIRTACELAQREPETVQLLAVSKTHPSERLR-EMYAAGQRAFGENYLQEALDKIDALQDLDIEWHFIGH-VQRNKTKHLA---EKFDWVHGVDRLIIAERLSNQRGDDQAALNICLQVNIDGQESKDGCAPE-DVAELVAQMSQLPKIKLRGLMVIPAPDNT--G----------AFADAKKLFDAVKVQHAHPEDWDTLSMGMSSDLEAAIA-AGSTMVRVGTALFGARDYSQKG 4V15 Chain:B ((31-261)) ---LDLPAFEANLRAMQAWAD---------RHEVALRPHAKAHKCPEIALRQLALGARGICCQKVSEALPFVAA-GI-R-DIHISNEVVGPAKLALLGQLARAAKISVCVDNAENLAQLSAAMTRAGAEIDVLVEVDVGQ--GRCGVSDDATVLALAQQARALPGLNFAGLQAYHGSVQHYRTREERAAVCRQAARIAASYAQLLRESG--I-ACDTITGGGTGSVEFDAASGVYTELQAGSYAFMDSDYG---

General information: TITO was launched using: RESULT: Template: 4V15.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1041 2942 2.83 13.88 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : 2.83 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.479

(partial model without unconserved sides chains): PDB file : Tito_4V15.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4V15-query.scw PDB file : Tito_Scwrl_4V15.pdb: