Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVETAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVHQDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEVADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAVEVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGETLSLQEFAALSNAMSENMQ 1QAO Chain:A ((9-243)) ----------------------------SQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKLCKTTENKLVDHDNFQVLNKDILQFKFPK--------NQSYKIFGNIPYNISTDIIRKIVFD-SIADEIYLIVEYGFAKRLLNTKR-----SLALFLMAEVDISILSMVPREYFHPKPKVNSSLIRLNRKKSRI-SHKDKQKYNYFVMKWVNKEYKKIFTK------------NQFNNSLKHAGIDD---LNNISFEQFLSLFNSYKLFN-

General information: TITO was launched using: RESULT: Template: 1QAO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1129 -158550 -140.43 -674.68 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -140.43 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.480

(partial model without unconserved sides chains): PDB file : Tito_1QAO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QAO-query.scw PDB file : Tito_Scwrl_1QAO.pdb: