Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence PGNRGSKLSPISSSISS-------PESLSDEEFEKF---CCVYIVNLGKPDQREWPVLTGKE-----VWFEHKRKKYDVMAFDSCNLVWGR-----RGEPKGVTFEFLETRTANKDGTC 1WI8 Chain:A ((81-184)) -GSSGSSGSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLNISAVRLPR-EPSN----PERLKGFGYAEFEDLDSLLSALSLNEESLG-NKRIRVDVADQA-------QDKDSGPSSG-

General information: TITO was launched using: RESULT: Template: 1WI8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 254 27913 109.89 332.30 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 109.89 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.436

(partial model without unconserved sides chains): PDB file : Tito_1WI8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WI8-query.scw PDB file : Tito_Scwrl_1WI8.pdb: