Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence LCTTIQKGQIFRNILTCMSEFYIKEEFSYTVCNGKNYASPNRTILCIW-EGHIIHVRLDERCNWTRLEGDQTEELESQNVEFKVLQKCVASKYKLDPPHAWDAGHGVKLG---- 1AYA Chain:A ((1-101)) MRRWFHPNITGVEAENLLLTRGVDG--SFLARPSKS--NPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEK---------FATLAELVQYYMEHHGQLKEKNGDVIELKYPLN

General information: TITO was launched using: RESULT: Template: 1AYA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 390 -6787 -17.40 -70.70 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -17.40 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.388

(partial model without unconserved sides chains): PDB file : Tito_1AYA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1AYA-query.scw PDB file : Tito_Scwrl_1AYA.pdb: