Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --CFVAIVSDDPRGPVLASKRFEGNREVSF---DGYDIVLE-----LGWD-CYAIKKSGTI--P-HGYHINIASGVDEPRVGVCNVYNDRTEPRRRNLHTQPT--SN---------- 1VCK Chain:A ((4-107)) IWLKVCAASDMQPGTIRRV-NRVGAAPLAVYRVGDQFYATEDTCTHGIASLSEGTLDGDVIECPFHGGAFNVCTG--MP----------ASSPCTVPLGVFEVEVKEGEVYVAGEKK

General information: TITO was launched using: RESULT: Template: 1VCK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 320 -1631 -5.10 -20.90 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -5.10 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.334

(partial model without unconserved sides chains): PDB file : Tito_1VCK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VCK-query.scw PDB file : Tito_Scwrl_1VCK.pdb: