Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence GCEVLISKKSGGDGPVKSSCIPKSGSKVIVINGKTVTVSADGSCKF-------SSKDLDPSLAMKFEGDCIGI- 3LKX Chain:A ((25-90)) -----VNNISG----IEEVNMFTNQGTVIHFNNPKVQASLANTFTITGHAETKQLTEMLPSILNQLGADSLTSL

General information: TITO was launched using: RESULT: Template: 3LKX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 169 -6255 -37.01 -109.74 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -37.01 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.591

(partial model without unconserved sides chains): PDB file : Tito_3LKX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LKX-query.scw PDB file : Tito_Scwrl_3LKX.pdb: