Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MCAAQMPPLAHIFRGTFVHSTWTCP-MEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCFKPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEH-RFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQK------NYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGY-SYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV 3LNP Chain:A ((21-444)) ------AHADLRINSHWIIPIENT-VSNILIDHCLLIK-DGIILAIEPQSSCQI--------PATETLDLGQQVLMPGWVNAHGHAAMSLFRGLADDLPLMTWLQEHVWPAEAQHVD-EHFVKQGTELAIAEMIQSGTTTFADMYFYPQ----QSGEAALAAGIRAVCFAPVLDFP---TNYAQ---NADEYIRKAIECNDRFNNHPMNEQGLVQIGFGPHAPYTVSDEPLKEITMLSDQLDMPVQIHLHETDFEVSESLETF-N-KRPTQRLADIGFLNERVSCVHMTQVDDGDIKILQKTGASIIHCPESNLKLASGFCPIAKLSAANIPLAIGTDGAASNNDLDMFSETKTAALLAKGVS---QDASAIPAIEALTMATLGGARALGIDDITGSLKPGKAADIQAIDLNTLS-S----------QPVFDPVSHMVYCTKSTQVSHVWVNGRCLLKNGEL-

General information: TITO was launched using: RESULT: Template: 3LNP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2635 -4169 -1.58 -10.17 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -1.58 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.498

(partial model without unconserved sides chains): PDB file : Tito_3LNP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LNP-query.scw PDB file : Tito_Scwrl_3LNP.pdb: