Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDSAIQIIHQNIHQRQSIGQLVEPAPNTDQLELAFQAALTAPDHHRLKPTRFVIVSGD-QRAAFGEVLAKALVDLGESDPAQLERVKQHPFRAPLLILALTQLQDHPKVPHFEQILSTGAAVQNLLLSLQAQGFSTMWRSGAVVE--SNWLKQHLGLQPHDLISGIIYVGTAAKAIAPRADIDSKEFVKVWQA 3M5K Chain:B ((5-167)) -----ENQTLETILNRKSVRKYKDRPVEKEKIDKLIRAGMAAPSSRDRRPWEFIIVTDRKALDTMAEGLP----------------FARMLKETRQAIVVCGDTIK----SSNAWFLDCSAASQNLLLAAESMGLGAVWTAVYPYPDRIEIVRKELRLPDHIMPLNVIPVGYPMQKETPKNKYNVQQI------

General information: TITO was launched using: RESULT: Template: 3M5K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 757 -55016 -72.68 -343.85 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.73 3D Compatibility (PKB) : -72.68 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.413

(partial model without unconserved sides chains): PDB file : Tito_3M5K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3M5K-query.scw PDB file : Tito_Scwrl_3M5K.pdb: