Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIERTLSIVKPDAVSKNHIGEIFARFEKAGLKIVATKMKHLSQADAEGFYAEHKERGFFGDLVAFMTSGPVVVSVLEGENAVLAHREILGATNPKEAAPGTIRADFAVSIDENAAHGSDSVASAEREIAYFFADNEICPRTR 4HR2 Chain:B ((6-145)) -ALERTLSIIKPDAVAKNVIGQIYSRFENAGLKIVAARMAHLSRADAEKFYAVHAERPFFKDLVEFMISGPVMIQVLEGEDAILKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAPETARVEIAFFFPEMNVYSR--

General information: TITO was launched using: RESULT: Template: 4HR2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 676 -52730 -78.00 -376.64 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.90 3D Compatibility (PKB) : -78.00 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.90 QMean score : 0.488

(partial model without unconserved sides chains): PDB file : Tito_4HR2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HR2-query.scw PDB file : Tito_Scwrl_4HR2.pdb: