Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDGAMQGSYATALLKQQQLPESFQFYFKQKQHLSNTQELHQLHELVRPRLKIAIVTETWPP---EINGVALSLLQLCQGLQKQGHKILLVRPEQKAKCHDF---LPE-QECLVMSQAIPK-YP-TLQFGWPQ-YLKVSK--AFEKFVPDVVHIVTEGPLGLTAMQAAKAKDIPVSSGFHSPFQDFSRFFDLAFLVKPIQKYLCWFHNNTQVTCVPSKDTEEALRG-FGITC-PLVVVGRGVDTTRFSPKHR--SENLRQQWGVDSDTRVMLYVGRLSPEKEVQLIVESYAAMQNIQQQ--KTKLVVVGDGPDLARLKALPEA----KNVIFTGSLCGHDLAVAYASADVFVFASQVETFGNVVLEAMASGLPVIAYDYACAHQYLIHGVNGWLSPLGHKNHFIQQIYQLPS-IQQLREMGIQACHKVQQSGWQLPVQQLEQAFYQVVKELSADFT 3C48 Chain:B ((21-431)) -------------------------------------------------MRVAMISMHTSPLQQ---GMNVYILSTATELAKQGIEVDIYTRATRPSQGEIVRVAENLRVINIAAGPYEGLSKEELPTQLAAFTGGMLSFTRREKVTYDLIHSHYWLSGQ-VGWLLRDLWRIPLIHTAHTLAAVK------TPESEARRICEQQLVDNADVLAVNTQEEMQDLMHHYDADPDRISVVSPGADVELYSPGNDRATERSRRELGIPLHTKVVAFVGRLQPFKGPQVLIKAVAALFDR-DPDRNLRVIICGGPS---TYRHMAEELGVEKRIRFLDPRPPSELVAVYRAADIVAVPSFNESFGLVAMEAQASGTPVIAARVGGLPIAVAEGETGLLVDGHSPHAWADALATLLDDDETRIRMGEDAVEHARTFSWAATAAQLSSLYNDAIANENV---

General information: TITO was launched using: RESULT: Template: 3C48.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1981 -15241 -7.69 -41.64 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : -7.69 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.557

(partial model without unconserved sides chains): PDB file : Tito_3C48.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C48-query.scw PDB file : Tito_Scwrl_3C48.pdb: