Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MENKKPYGTVLIKASKILDYLAE-NQDVSLQTIAKGVGMTSSTVLKILDTLLMIGYVNKNSE-KNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETIHLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLEKHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKN-EQIIGAFSVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK 2XRN Chain:B ((14-252)) -------IQVIARAASIMRALGSHPHGLSLAAIAQLVGLPRSTVQRIINALEEEFLVEALGPAGGFRLGPALGQLINQA--QTDILSLVKPYLRSLAEELDESVSLASLAGDKIYVLDRIVSER-ELRVVFPIGINVPAAATAAGKVLLAALPDETL-QAALGEQLPVLTSNT-LGRKALVKQLSEVRQSGVASDLDEHIDGVSSFATLLDTYLG--YYSLAIVMPSSRASK-QSDLIKKALLQSKLNIERAIG-

General information: TITO was launched using: RESULT: Template: 2XRN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1115 22835 20.48 96.76 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain B : 0.75 3D Compatibility (PKB) : 20.48 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.490

(partial model without unconserved sides chains): PDB file : Tito_2XRN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XRN-query.scw PDB file : Tito_Scwrl_2XRN.pdb: