Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEGVRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTFDLG--KACDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKFAVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAKMIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK 1Q7B Chain:C ((2-188)) -NFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYL----GANGKGLMLNVTDPASIESVLEKIRAEFGEVDILVNNAG--ITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGITVNVVAPGFIETDM----------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1Q7B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 960 -75023 -78.15 -405.53 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain C : 0.72 3D Compatibility (PKB) : -78.15 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_1Q7B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q7B-query.scw PDB file : Tito_Scwrl_1Q7B.pdb: