Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------SSSDTDSDSSPDRGLSRMCCVYKIHPGGNIWSTKKGE---QAWFRRRFSKYEVMAYDRCNLEWGFSGKP--RGLTFEFLWD----------------KEAAADGTC 1A77 Chain:? ((209-316)) ISLDDLIDIAIFMGTDYNPGGVKGIGFKR---AYELVRSGVAKDVLKKEVEYYDEIKRIFKEPKVT--DNYSLSL---KLPDKEGII-KFLVDENDFNYDRVKKHVDKLYNLIANKT-

General information: TITO was launched using: RESULT: Template: 1A77.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 199 15304 76.90 204.05 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 76.90 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.183

(partial model without unconserved sides chains): PDB file : Tito_1A77.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1A77-query.scw PDB file : Tito_Scwrl_1A77.pdb: