Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIYRLSMSLIANT-TVVRGRFLDIQQTVSEPTDIPNQVRYLEDGVLISEHGKIKWFGAWEDAQQHLPAGVEVQHYPEQLIVPGFIDTHIHFPQTEMVGAYG---EQLLSWLNTYTFP-----TEIQFQDKTYASEIAQFFVQELLKHGTTTALVFCTVHP-----ESVDALFEAAERVQMRLIAGKVLMDRNA-PEAL-----CDTPETAYSNTKALIEKWHG-K--GRALYAITPRFAPTSTPEQLERAGQLKQEFPDVYVHTHLSENKDEIAWVKSLFPEQAGYLDVYQHYGLTGKRSVFAHCVHLEDEEWQCMHDTQSAIAFCPTSNLFLGSGLFPLKKTWEKQVKVGLGTDIGAGT-SFSLLQTVNEAYKVQQLQ-----GDKLSAYEALYHATLGGAKALDLQDQLGNFNIGKEADFVVLNLKPTALQELRQTKSKSVEDSLFALFTLGDDRNIEATYIYGNRAYQKETAK 3LS9 Chain:B ((1-436)) -------MILIRGLTRVITF---------------DDQERELEDADILIDGPKIVAVGKDLSD----RSVSRTIDGRGMIALPGLINSHQHLYEGAMRAIPQLERVTMASWLEGVLTRSAGWWRDGKF-GPDVIREVARAVLLESLLGGITTVADQHLFFPGATADSYIDATIEAATDLGIRFHAARSSMTLGKSEGGFCDDLFVEPVDRVVQHCLGLIDQYHEPEPFGMVRIALGPCGVPYDKPELFEAFAQMAADY-DVRLHTHFYEPLDAG-MSDHL--YGMTPWRFLEKHGWASDRVWLAHAVVPPREEIPEFADAGVAIAHLIAPDLRMGWGLAPIREYLDAGITVGFGTTGSASNDGGNLLGDLRLAALAHRPADPNEPEKWLSARELLRMATRGSAECLGRP-DLGVLEEGRAADIACWRLDGVDRV--------GVHDPAIGLIMTGLSDRASLVVVNGQVLVENERP-

General information: TITO was launched using: RESULT: Template: 3LS9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2410 -33337 -13.83 -81.91 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.71 3D Compatibility (PKB) : -13.83 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.449

(partial model without unconserved sides chains): PDB file : Tito_3LS9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LS9-query.scw PDB file : Tito_Scwrl_3LS9.pdb: