Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence PGNRGSKLSPISSSISS-------PESLSDEEFEKFCCVY--IVNLGKPDQREWPVLTGKEVWFEHKRKKYDVMAFDSCNLVWGRRGEPKGVTFEFLETRTANKDGTC----- 1WEX Chain:A ((1-104)) -GSSGSSGSHHKVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVE-----FENIDSAKECVTFAADVPVY-IAGQQ--AFFNYSTSKRITRPGNSGPSSG

General information: TITO was launched using: RESULT: Template: 1WEX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 366 13275 36.27 147.49 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 36.27 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.384

(partial model without unconserved sides chains): PDB file : Tito_1WEX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WEX-query.scw PDB file : Tito_Scwrl_1WEX.pdb: