Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------QVFGCFV----QMSVRTQDSKDETNISSGGYLLTTNPGQLVFTDGNNNITVKVDKD-----CQSAGISYHRSEVHFTALQKLSENGGPFEFDQPL-IELQ--- 1GH7 Chain:A ((1-111)) EETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVTLIRRVN------EDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLGTRLTVTL

General information: TITO was launched using: RESULT: Template: 1GH7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 291 -1091 -3.75 -12.98 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -3.75 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.158

(partial model without unconserved sides chains): PDB file : Tito_1GH7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GH7-query.scw PDB file : Tito_Scwrl_1GH7.pdb: