Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MCAAQMPPLAHIFRGT-FVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCFKPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSI--DLPLLEWLTKYTF-----PAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHT-----DSSLLLADITDKFGQRAFVGKVCMDLNDTFP-----EYKETTEESIKETERFVSEMLQ-KNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGY-SYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV 3LS9 Chain:A ((1-436)) ---------MILIRGLTRVITFDD-QERELEDADILID-GPKIVAVGKDLSDR---------SVSRTIDGRGMIALPGLINSHQHLYEGAMRAIPQLERVTMASWLEGVLTRSAGWWRDGKFG-PDVIREVARAVLLESLLGGITTVADQHLFFPGATADSYIDATIEAATDLGIRFHAARSSMTLGKSEGGFCDDLFVEPVDRVVQHCLGLIDQYHEPEPFGMVRIALGPCGVPYDKPELFEAFAQMAADYDVRLHTHFYEPLDAG-MSDHLY-G-MTPWRFLEKHGWASDRVWLAHAVVPPREEIPEFADAGVAIAHLIAPDLRMGWGLAPIREYLDAGITVGFGTTGSASNDGGNLLGDLRLAALAHRPADP-NEPEKWLSARELLRMATRGSAECLGRP-DLGVLEEGRAADIACWRLDGVD--R---------VGVHDPAIGLIMTGLSDRASLVVVNGQVLVENERP-

General information: TITO was launched using: RESULT: Template: 3LS9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2498 -51028 -20.43 -122.66 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -20.43 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.479

(partial model without unconserved sides chains): PDB file : Tito_3LS9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3LS9-query.scw PDB file : Tito_Scwrl_3LS9.pdb: