Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYG--FASVCVNPTWVEHAKKGLEG---TDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNLALVESDIRAVVEA-SGDKLVKVIIEACLLTDQEKIV-VCQLAQKAGADFVKTSTGFSTGGATIADVTLMRETV---GSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADGDY 5C5Y Chain:C ((15-229)) ------MDLTSLTNTETDQEIIDLCRQAKSPAGETAAICIFPRFIPVAKKALKAQQTPHIKIATVTNFPQGNDDLDIALAETRAAVAYGADEVDLVFPYRALIQGNETIGFDMVKVCKQACSGNAKLKVIIETGELKSEELIRKASEIAINAGADFIKTSTGKVAINATPEAAKVMLTVIKNKNTAVGFKPAGGVRNADDAAIYLDLADN---------ILGNEWADANH

General information: TITO was launched using: RESULT: Template: 5C5Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1123 -16603 -14.78 -80.99 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain C : 0.75 3D Compatibility (PKB) : -14.78 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.509

(partial model without unconserved sides chains): PDB file : Tito_5C5Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5C5Y-query.scw PDB file : Tito_Scwrl_5C5Y.pdb: