Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHKTDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRV------------PAGGALAVDRDGFSQMVTEKVANHPLIEVVRDEITEL-----------------PTDVITVIATGPLTSD-------ALAEKIHALNDGDGFYFYDAAAPIIDVNTIDMSKVYLKSRYDKGE-----------AAYLNAPMTKQEFMDFHEALVNAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQTYRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETT-AIGSLAHYITHA---------------------DSK--HFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV 3CES Chain:B ((5-481)) -DPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNID---------TLGQMSCNPAIGGIG----KGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGSIPLSRRLRE-LPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYIT--HTNEKTHDVIRSNL----------------SIED------KVMRFA---------------------DRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPR-DLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEIGRELGLVDDERWARFNEKLENIERERQRLK---------

General information: TITO was launched using: RESULT: Template: 3CES.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2285 -2673 -1.17 -7.15 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -1.17 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.400

(partial model without unconserved sides chains): PDB file : Tito_3CES.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CES-query.scw PDB file : Tito_Scwrl_3CES.pdb: