Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMKRTWRNSFVTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLVVMEMVSDKGIQYNN------EK--------TLHMLHID-EGENPVSIQLFGSDEDSLARAAEFIQENTKTDIVDINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVENALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGD----IRTVQEAKQRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLINLKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA 4XP7 Chain:A ((13-319)) ---------------------SLCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDFVAPDDRVVFRTCEREQNRVVFQMGTSDAERALAVARLVEN--DVAGIDVNMGCPKQ---------ALLSDPDKIEKILSTLVKGTRRPVTCKIRILPSLE-DTLSLVKRIERTGIAAIAVHGRKREERPQHPVSCEVIKAIADTL-SIPVIANGGSHDHIQQYSDIEDFRQATAASSVMVARAAMWNPSIFLKEGL-------------RPLEEVMQKYIRYAVQYDN---HYTNTKYCLCQMLREQLE-SPQGRLLHAAQSSREICEA------

General information: TITO was launched using: RESULT: Template: 4XP7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1567 12547 8.01 44.97 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 8.01 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.538

(partial model without unconserved sides chains): PDB file : Tito_4XP7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4XP7-query.scw PDB file : Tito_Scwrl_4XP7.pdb: