Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTFVDAARSFRTQFDLNFSEKIIVDFFAGGGGASTGLEMGLNRPVYVAVNHNPKAISMHEANHPHAKHYIQDVFAVDPIDICDGHQVGWFHASPDCTHHSQAAGGQPRKKEIRDLSWVVLKFAGKVKPDVISLENVKQILGWGPLIAKRDKATGRVITLDKININGKKVNRIAEPGERVPRHNQFLVPNPKKKGKTWKHFVRSLEQLGYEVEWQKNIIAADFGAPTKRERLFLIARCDGQPIVWPEKYFSKKPKGNLKKWRSTVECVDFSDLGNSIFDRPQGPLADATLKRIAKGIQKYVIETKEPFFVNSSTPFIGRDFRTSFGHDIREPLATTTAGYGGHSSLISPILVPFITEFANASQQRNWSIDEPLSTICAQVKGGHHGLVTAKLSKDNYKGALRVAAFLINYYGNGDARSITEPMDTITTKDRLVLVTVWIKGEPWAIVDICIRMLKPRELFRAQGVPDSYVIEYGSDGKPLSKKDQVFMVGNSVSPYPMAAIARANNPFITQQIKGAA 6MHT Chain:A ((1-327)) ----------MIEIKDKQLTGLRFIDLFAGLGGFRLALESC-GAECVYSNEWDKYAQEVYEMNFG--EKPEGDITQVNEKTI---PDHDILCAGFPCQAFSISGKQKGFEDSRGTLFFDIARIVREKKPKVVFMENVKNFA-------------------------------------------------SHDNGNTLEVVKNTMNELDYSFHAKVLN-ALDYGIPQKRERIYMICFR--------------------------------NDLNIQNFQFPKPFELNTFVKDLLLP-----------------------------------------------------------DSEVEHLVIDRKDLVMTNQEIEQTTPKTVRLGIVGKGGQGERIYSTRGIAITLSAYGGGIFAKTGGYLVN---------------GK--------TRKLHPRECARVMGYPDSYKVH-PS------TSQAYKQFGNSVVINVLQYIAYNIGSSLNFKPY---

General information: TITO was launched using: RESULT: Template: 6MHT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1701 -117874 -69.30 -360.47 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -69.30 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.306

(partial model without unconserved sides chains): PDB file : Tito_6MHT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6MHT-query.scw PDB file : Tito_Scwrl_6MHT.pdb: