Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKLVVFSGAGMSAESGISTFRDSNGLWENYDIQQVATPEAWERNPALVQRFYNERRKNILEAQPNEAHQYIAKL-----QDHYDVQVITQNIDDPHERAGSQNVLHLHGNIRLAKSSGPDAQYTTQFYEVNGWKLDLEQDFCP----NGYP-------------------------LRPHVVWFGEAVPA--YEEAIRLVQSADIFIVIGSTLSVYPVAALVHEIPHYSKAYYIAPQADHSRVPPQYKLLNMTATEGMHELFNQLTS 4UTX Chain:A ((26-239)) ---IAIITGAGVSAESGVPTFRGPGGFWRKWQAQDLATPEAFSRDPSLVWEFYHYRREVMRSKMPNPAHLAIAECEARLGQQGRSVVIITQNIDELHHRAGSKHVYEIHGSL-----------FKTRCMSCGEVKANHKSPICPALDGKGAPDPNTKEARIPVELLPRCERKSCNGLLRPHVVWFGETLDSDILTAVERELEKCDLCLVVGTSSIVYPAAMFAPQV------------------------------------------

General information: TITO was launched using: RESULT: Template: 4UTX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 807 -22499 -27.88 -127.84 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -27.88 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.528

(partial model without unconserved sides chains): PDB file : Tito_4UTX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4UTX-query.scw PDB file : Tito_Scwrl_4UTX.pdb: