Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRIILLGPPGAGKGTQAQLICKRYNIPQISTGDMLRAAIREGTELGLKAKSVMESGGLVSDELIIGLVKERIAQPDCVNGCIFDGFPRTIPQAEALEK----EGISIDHVIEIDVPDEEIVKRLSGRRQHPASGRVYHVVYNPPKVEGKDDETGEDLVQRPDDQEETIRKRLASYHTETEQLVGFYQGRAASGENAPTYDKLDGLRTIEDVQKDLFNILDK 3FB4 Chain:A ((1-212)) MNIVLMGLPGAGKGTQAEQIIEKYEIPHISTGDMFRAAIKNGTELGLKAKSFMDQGNLVPDEVTIGIVHERLSKDDCQKGFLLDGFPRTVAQADALDSLLTDLGKKLDYVLNIKVEQEELMKRLTGRWICKTCGATYHTIFNPPAVEGICDKDGGELYQRIDDKPETVKNRLDVNMKQTQPLLDFYSQKGVLKD-------IDGQQDIKKVFVDINDLL--

General information: TITO was launched using: RESULT: Template: 3FB4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 950 -47053 -49.53 -226.22 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : -49.53 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_3FB4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FB4-query.scw PDB file : Tito_Scwrl_3FB4.pdb: