Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKTATALTLACSLLSVMSISQAQAADNIDVSFQTILQQERNWAGLQSKSLKVGDITWSYSEGGSSTKPTLLLIHGLAGSRDNWNRVAHYLTTNYHVIIPDLPGSGETIVSHDFDYSVPNLAEKLRRFVEAANLKGPIHIAGHSLGGSIALLYAGQYPFETKSLFLVDSGGIFRSANT--IYLKDLTYLKQLLVSKKG---DFNYLLKQTMFNP---PFIPREFLQAQEKLMIN-QAPQTQKL---V---DQLIALNKVYTPDSFAVLTKTIDAPTLILWGKQDKIINVEVANELKRLLKNAQPPVILENVGHMPILEAEQLVIQQYVPFLLKVETNQSSKTTTP 1CQW Chain:A ((9-292)) -----------------------------------------------PHYVEVLGERMHYVDVGPRDGTPVLFLHGNPTSSYLWRNIIPHVAPSHRCIAPDLIGMGKSDKPD-LDYFFDDHVRYLDAFIEALG-LEEVVLVIHDWGSALGFHWAKRNPERVKGIACMEFIRPIPTWDEWPEFARETFQAFRTADVGRELIIDQNAFIEGVLPKCVVRPLTEVEMDHYREPFLKPVDREPLWRFPNEIPIAGEPANIVALV--EAYMNWLHQSPVPKLLFWGTPGVLIPPAEAARLAESLPN-CKTVDIGPGLHYLQEDNPDLIGSEIARWLPGLAS---------

General information: TITO was launched using: RESULT: Template: 1CQW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1450 -108259 -74.66 -402.45 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -74.66 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_1CQW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1CQW-query.scw PDB file : Tito_Scwrl_1CQW.pdb: