Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQVYLVGGAVRDYLLGHSYQEKDYVVVGATPEHMLAQGFQP------VGKDFPVFLH---PETKEEYALARTERKSGQGYHGFQFFTDTTVSLEDDLIRRDLTINAIAMDQD----GKIYDPYGGQNDLENKILRHVSE-AFAEDPLRVLRVARFAARYFPYGFQIAPETLQLMQTMADSGELDALTPERVWKETSRALMENHADIYFQTLRDCGALKHLFPEIDALFGVPQRPEYHPEVDCGIHTLMSLQQACKSNYSLDVRFAVLVHDLGKALTPAKELPRHIMHEERGIKPVTQLCERLRVPTQTKQLALSVCKEHLKCHQI--MSLKPGTLWRLLQRLDVLRRPERVEAFVQACECDAKGRLGLEDRPYPQAQYMREAMQ-IVRSIKVQ-DLPENI-KGAEIGEMLIQYRIEALAEFKNQHQSLSHS 5HC9 Chain:A ((36-416)) -PVYVVGGFVRDLLLGIKNLDIDIVVE-GNALEFAEYAKRFLPGKLVKHDKFMTASLFLKGGLRIDIATARLEYYESPAKL-PDV---EMSTIKKDLYRRDFTINAMAIKLNPKDFGLLIDFFGGYRDLKEGVIRVLHTLSFVDDPTRILRAIRFEQRF---DFRIEETTERLLKQAVEEGYLERTTGPRLRQELEKILEEKNPLKSIRRMAQFDVIKHLFPKTYYTPSMDEK---------MENLFRNIPWVE-ENFGEVDRFYAVLHVFLEFY---------------DDESWKEVRDRYSLRRNLINEIRHVEKSAPALLEMLSERVPASFVYPLVKGVSN----ETICHFLAY----LSGEKE-----GLFKSYLLKIKNTKLEKINGEYLIRKGITSGKIIGEVLEKILMKKLDGDTRDEEEI---

General information: TITO was launched using: RESULT: Template: 5HC9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1530 -3119 -2.04 -8.61 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -2.04 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.475

(partial model without unconserved sides chains): PDB file : Tito_5HC9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5HC9-query.scw PDB file : Tito_Scwrl_5HC9.pdb: