Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNP-ERIAVAAVDQDELVGFIGAIPQYG----------ITGWELHPLVVESSRRKNQIGTRLVNYLEKEVAS-RGGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPNANGWDKPDIWMAKTIIPRPNSQ 4R3L Chain:A ((13-167)) -TLRNAR---MDDIDQIIKINRLTLPENY---PYYFFVEHLKEYGLAFFVAIVDNSVVGYIMPRIEWGFSNIKQLPSLVRKGHVVSIAVLEEYRRKGIATTLLEASMKSMKNDYNAEEIYLEVRVS-------------------------NYPAIALYEKLNFKKVKVLKGYYADGEDAYLMARPL-------

General information: TITO was launched using: RESULT: Template: 4R3L.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 613 -25918 -42.28 -181.24 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -42.28 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_4R3L.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4R3L-query.scw PDB file : Tito_Scwrl_4R3L.pdb: