Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEINYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLGQVASTSM--NYNSFQELNENP----IFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVTIPVDLGFEEIDEQPFSTAHTHKTSVILPE------EKDLLAALPYLEKAKKPVLYVGQGT-RNGFPQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGF-AGRVATKPGNEALAEADLILFVGSDFPF--GRAFFNPTAEFIQIDIDASKFGRRHETSLSILG-DANTALQRLVELGDARPADSWYLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIRLLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPE-KQVFTLSGDGGFAMVMQDIITQVKYQLPIINVVFSNDSFGFIEAEQEDT-EQKKFGVFLEDADFGKVGEALGANSFTVTEYSQLRFAFD--AAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLPVLNELYEKRL 1POX Chain:A ((1-542)) -TNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALSAERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPVLALIGQFGTTGMNM--DTFQE-M---NENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQGVAVVQIPVDLPWQQISAEDWYASANNYQTPLLPEPDVQAVTRLTQTLLA----AERPLIYYGIGAR-KAGKELEQLSKTLKIPLMSTYPAKGIVADRYPAYLGSAN-RVAQKPANEALAQADVVLFVGNNYPFAEVSKAFKNTRYFLQIDIDPAKLGKRHKTDIAVL-ADAQKTLAAILAQVSERESTPWWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDAIYSIDVGDINLNANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYP-ERQVFNLAGDGGASMTMQDLVTQVQYHLPVINVVFTNCQYGFIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVNKIEQLPDVFEQAKAIAQHEPVLIDAVITGDRP--L--------------------------------------

General information: TITO was launched using: RESULT: Template: 1POX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3072 -35486 -11.55 -68.11 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : -11.55 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.528

(partial model without unconserved sides chains): PDB file : Tito_1POX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1POX-query.scw PDB file : Tito_Scwrl_1POX.pdb: