Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNRQQIDVLVKQMNIDTAKGEVDARVQQIVVRLLGDLFQAIEDLDIQPSEVWKGLEYFTDAGQANELGLLAAGLGLEHYLDLRADEADAKAGMTGGTPRTIEGPLYVAGAPESVGFAHMDDGT-ETGKIDTLIIEGTVTDTDGNIIENAKVEVWHANSLGNYSFFDKSQSDFNLRRTIFTDADGKYVALTTMPVGYGCPPEGTTQALLNKLGRHGNRPSHVHYFVSAPGYRKLTTQFNIEGDEYLWDDFAFATRDGLVATAVDVTDPAEIQRRGLDHAFKHITFNIELVKEATAAPSTEVERRRASA 2XSU Chain:A ((10-312)) --QQIDALVKQMNVD-TAKGPVDERIQQVVVRLLGDLFQAIEDLDIQPSEVWKGLEYLTDAGQANELGLLAGGLGLEHYLDLRADEADAKAGITGGTPRTIEGPLYVAGAPESVGFARMDDGSESD-KVDTLIIEGTVTDTEGNIIEGAKVEVWHANSLGNYSFFDKSQSDFNLRRTILTDVNGKYVALTTMPVGYGCPPEGTTQALLNKLGRHGNRPSHVHYFVSAPGYRKLTTQFNIEGDEYLWDDFAFATRDGLVATATDVTDEAEIARRELDKPFKHITFNVELVKEAEAAPSSEVERRRASA

General information: TITO was launched using: RESULT: Template: 2XSU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1356 6384 4.71 21.14 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.95 3D Compatibility (PKB) : 4.71 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.95 QMean score : 0.621

(partial model without unconserved sides chains): PDB file : Tito_2XSU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XSU-query.scw PDB file : Tito_Scwrl_2XSU.pdb: