Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEEKKMKRFVRMGIDVGG---THTKAVAIDNATHEIIGKSSVKTT-HDDVRGVAAGVVQSFQNCLRENNISPEDVVFVAHSTTQAT-------NALIEGDVAKVGVIGMAKGGLEGFLAKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETIS---SLERERAEVLVSSMAFGVDNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTEDSVREAGVNVSLMIMRGD-----GGVMEINEMKKRPVLTMLSGPAASVMG--SLMYLRASNGVYFEVGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGPRSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANVLGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIM-EKSYAKIEPVILELADKYHLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALA-MVRDVVERIIPSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLTKEITTEEALELAAE---DMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKVQRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQLQLLMDLEVSTMEPEEEVIVVAGNIKQT 5FRP Chain:A ((3-691)) KGAVTKLKFNSPIISTSDQLISTNELLDRLKALHEELASLDQDNTDLTGLDKYRDALVS--RKLLKHKDVGIRAFTACCLSDILRLYAPDAPYTDAQLTDIFKLVLSQFEQLGDQENGYHIQQTYLITKLLEYRSIVLLADLPSSNNLLIELFHIFYDPNKSFPARLFNVIGGILGEVISEFDSVPLEVLRLIFNKFLTYNPNEIPEGLNVTS-------DCGYEVSLILCDTYSNRMSRHLTKYYSEIIHEATNDDNNSRLLTVVVKLHKLVLRLWETVPELINAVIGFIYHELSSENELFRKEATKLIGQILTSYS--DLNFVSTHSDTFKAWISKIADISPDVRVEWTES-IPQIIATREDISKELNQALAKTFIDSDPRVRRTSVMIFNKVPVTEIWKNIT-----NKAIYTSLLHLAREKH-----KEVRELCINTMAKFYSNSLNEIERTYQNKEIWEIIDTIPSTLYNLYYINDLNINEQVDSVIFEYLLPFE----------PDNDKRVHRLLTVLSHFDKKAFTSFFAFNARQIKISFAISKYIDFSKFLNNQESMS-----SSQGPIVMNKYNQTLQWLASGLSDSTKAIDALETIKQFNDERIFYLLNACVTNDIPFLTF--KNCYNELVSKLQ--------------------TPSIMPRDIAKVIQILLFRASPIIYNV---SNISVLLNLSNNSDAKQLDLKRRILDDISKVNPTLFKDQIRTLK-

General information: TITO was launched using: RESULT: Template: 5FRP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2793 92415 33.09 141.96 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 33.09 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.188

(partial model without unconserved sides chains): PDB file : Tito_5FRP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5FRP-query.scw PDB file : Tito_Scwrl_5FRP.pdb: